The first line has been breached

Trample When this creature enters, destroy target noncreature permanent. Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

You can't get poison counters. Creatures you control can't have -1/-1 counters put on them. Creatures your opponents control lose infect.